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Complete Process and Product Characterisation Group
The NIBRT Complete Process and Product Characterisation Group is a world leading group in the application of HPLC and MS technologies for quantitative glycan monosaccharide composition analysis and exoglycosidase sequencing of site-specific glycosylation. The technology provides a service that supports the drug development pipeline of leading pharmaceutical companies.
NIBRT
National Institute for Bioprocessing Research and Training (NIBRT) is located in Dublin, Ireland with a mandate to support the development of the bioprocessing industry by: Training highly skilled personnel for the bioprocessing industry. Conducting world-class research in key areas of bioprocessing. Providing flexible, multi-purpose bioprocessing research and training facilities. For further information please refer to www.nibrt.ie or email.
NIBRT’s training mission is to develop and deliver world class training solutions that are specifically focused on the needs of the bioprocessing industry. The Institute’s research strategy is focused on the design, development and optimisation of bioprocesses for the safe and economic manufacture
of biopharmaceuticals.
Waters Center of Innovation
Waters Centers of Innovation Program recognizes analytical scientists facilitating breakthroughs in health and life science research, food safety, environmental protection, sports medicine and many other areas. Through the partnership with Waters, NIBRT was awarded with the Waters Center of Innovation in the area of glycobiology research. Prof. Pauline Rudd, NIBRT’s principal investigator, and her team are working with Waters mass spectrometry based systems to take challenging glycan characterization to the next level. By improving understanding of glycan chemical and molecular structure, scientists can better understand safety and efficacy profiles for a potential molecule, leading directly to novel biotherapeutic options. Waters and NIBRT have established the Complete Product and Processing Characterization Facility (CPPCF) for hands-on laboratory based scientific training and retraining of ‘fit-for-purpose’ biopharmaceutical analysis, including protein and peptide characterization. The CPPCF’s goal is to provide comprehensive training of industry and governmental technicians and scientists to help the burgeoning industry develop advanced biotherapeutic characterization. For more information click here.
Agilent Thought Leader Award
Professor Pauline Rudd has received an Agilent Thought Leader Award in support of her emerging glycomics research. The award includes a grant of funding and instruments to the National Institute for Bioprocessing Research and Training (NIBRT) in Dublin, Ireland. The goals of the research are to develop novel approaches to analyze protein glycosylation which will assist in the characterization of recombinant protein drugs, and to study potential glycan biomarkers associated with disease using liquid chromatography/mass spectrometry. For more information click here
Special Recognition Award winner in the 2012 Facility of the Year Awards (FOYA) program
The FOYA program is the pharmaceutical industry’s premier awards program dedicated to celebrating innovation and accomplishments in facility design, construction, and operation. NIBRT have been awarded a Special Recongition Award for Novel Collaboration. For more information click here.
Funding
NIBRT is funded by the IDA Ireland with a mandate to support the development of the existing bioprocessing industry in Ireland and to attract additional bioprocessing companies to Ireland. Construction of NIBRT’s new state-of-the-art facility which will be located in UCD’s Innovation Park is scheduled to commence in late 2009.
Key areas of research
- Protein expression systems and cell biology
- Post translational modification and biopharmaceutical drug design
- Upstream processing
- Downstream processing and formulation
- Product Analytics
Outputs
As well as Masters courses and customised programmes, NIBRT develops and delivers world class training solutions specifically focused on the needs of the bioprocessing industry. Modules can be delivered remotely, online and via distance learning to provide the flexibility that is required by clients.
